The urban metabolism approach has been proposed for more than half a century. Its applications, especially the indicator analysis, are applied in many domains. By the indicator analysis of an area's metabolism, development strategies and urban design outcomes can be proposed from the perspectives of resource consumption and waste production. Since a large number of activities of metropolitan areas' municipalities have started to integrate urban metabolism issues with urban development, there seems to be a substantial gap in the urban metabolism indicator study of metropolitan areas and corresponding local public administrations. This study is aimed at developing urban metabolism indicator framework, to support the urban design procedure of metropolitan area. To put the proposed indicators into practice, a set of urban metabolism indicators is proposed to be adopted in Amsterdam Metropolitan Areas. The selection process is conducted by using the Delphi method. In doing so, 2-round questionnaire is responded by qualified experts to select the most relevant and practicable urban metabolism indicators. Then, these selected indicators are generated and grouped into different categories. By organising the Peri-Urban Living Lab (PULL) Workshop Amsterdam Metropolitan Area, the potential usage of these indicators will be evaluated. In the meantime, PULL stakeholders will categorise and prioritise these indicators from different fields. Afterwards, the urban metabolism indicator framework will be established based on the perspectives from urban metabolism related stakeholders. This exploration contributes to the field of practical application of urban metabolism indicators in municipalities of metropolitan areas.