This chapter discusses integrated approaches to the management of risks related to extreme weather and climate change. This is done with the Loss and Damage (L&D) mechanism of the UNFCCC in mind. Relevant insights are provided for climate policy negotiators and policymakers on how risk management and adaptation interact with L&D solutions, and vice versa, on how L&D-related activities can support risk reduction and adaptation in vulnerable countries. Particular attention is devoted to how risk management can help society confront the impacts of weather disasters in relation to anthropogenic climate change. A holistic view of risk management is presented by discussing: the state-of-the art of risk assessment methods; (cost-benefit) evaluations of risk management options; household-scale risk reduction strategies; insurance schemes for residual risk and their relations with risk reduction; and the design of adaptation pathways to cope with uncertain timing and intensity of climate change impacts. Each topic is illustrated with concrete case studies. Finally, conclusions are drawn on the links between disaster risk management, climate adaptation and the L&D mechanism.